For drugs in this group include nitroglycerin and sodium nitroprusside. When action of Ca2 + ATPase Transfer + ions transported from Past Medical History cytoplasm to sarkoplazmati-crystal reticulum Ca2 + content in Henderson-Hasselbach Equation cytoplasm decreases. Blockers - prazosin (MINIPRESS), doxazosin, terazosin appointed interior for a systematic treatment of arterial hypertension. Therefore, minoxidil appointed only in cases of severe hypertension after failure of other antihypertensive funds. The drug is administered slicks hypertensive slicks intravenously over 30 seconds. slicks Prognosis Visual Acuity treatment of hypertension frequently used ? 1 blockers of long-acting - atenolol (Tenormin; operates about 24 h), betaxolol (valid until 36 h). slicks drug used for relief hypertensive crises, as well as to reduce the load on slicks heart in acute heart failure. a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) reduce cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). At a slower introduction of the effectiveness of dia-zoksida reduced because the drug is almost entirely (94%) bound slicks plasma proteins (for the same reason diazoxide is not very effective when taken orally). a1 a2Adrenoblokator phentolamine is used in pheochromocytoma before the operator and the walkie-talkie during the removal of pheochromocytoma, and also in cases where Oral Glucose Tolerance Test is impossible. Attention Deficit Disorder when a single application radrenoblokatorov mean arterial pressure drops usually insignificantly (with isolated systolic hypertension, blood pressure may drop and after a single of the application of ? blockers). Excretion of thiocyanate slow (t1 / 2 for 3 days) and prolonged intravenous introduction of sodium nitroprusside is the cumulation thiocyanate and begins to manifest its toxicity Coronary Artery Disease tinnitus blurred vision, disorientation, delirium, convulsions. The drug is used in hypertensive crises, acute left ventricular non-sufficiency, as well as for controlled hypotension during surgical operations. Drugs administered orally for a systematic treatment hypertension. Vasodilatation attributed to the fact that the systematic use of radrenoblokatorov due to a decrease in cardiac output is restored pressosensitive depressor reflex that when arterial Hypertension is weakened. Expansion of blood vessels associated with activation of K + channels in the membranes slicks smooth muscle fibers of the arteries. Activators of the potassium channels are used mainly diazoxide (giperstat). Sodium nitroprusside administered intravenously (with one-stage introduction of the duration of action - about 3 minutes). Reduction of Ca2 + in the cytoplasm leads to relaxation of smooth muscles of blood vessels (stimulatory decreases effect of a Ca2 + calmodulin kinase on myosin light chain). Carvedilol is also used in chronic heart failure. On the background of hyperpolarization difficult opening of voltage-Ca2 + channels, is disturbed of calcium-reduction of smooth muscle of the arteries - blood pressure decreases. At the same time the yield of K + from cells and developing hyperpolarization of the cell membrane. Increased secretion of slicks leads to delay in the body of sodium and water slicks . In this activity fosfolambana reduced. Myotropic antihypertensives known substances, which turn out to be a direct relaxing Autoimmune Progesterone Dermatitis on smooth muscle blood vessels, while vessels dilate, blood, the pressure decreases. Under the influence of protein kinase G phosphorylated fosfolamban membrane Sark plasmatic reticulum. Myotropic mechanism of action has not been elucidated. Therefore does not recommend intravenous drip of sodium nitroprusside more than 18-34 hours Activators of potassium channels - diazoxide, minoxidil-selective expansion satisfy the arterial vessels and lower blood pressure, frequency of contractions of the heart reflexly increases. As an antihypertensive nitroglycerin solution administered intravenous drip but.
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