In the form of nail polish "Lotseril" is used in onihomikozah. Under the influence of the virus thymidine kinase is Tender Loving Care of acyclovir - Acyclovir is formed undiverted Enzymes cells produce further phosphorylation to undiverted triphosphate, which is: I) inhibitor induces DNKpolimerazu virus, 2) is incorporated in Virus DNA. Assign locally at undiverted and superficial candidiasis. Applied topically as a cream, solution for external use in dermatomycosis. The drug is well absorbed in the same-ludochnokishechnom tract, concentration in the cerebrospinal liquid is 60-80% of plasma concentrations. Acyclovir (Zovirax) - a synthetic analogue of guanine. Well into the skin and undiverted appendages. Flucytosine is effective in cryptococcosis, systemic candidiasis. Tsiklopiroks similar in effect to the azole. Side effects of flucytosine: nausea, vomiting, diarrhea, liver damage, bone marrow suppression (may be offset by the appointment undiverted agents colony-stimulating factor), alopecia. Triazoles compared to the imidazoles act on lanosterol mushrooms more selectively, and in general more effective (effective fungicide) and less toxic (do not affect significantly on endocrine function). Assign inside capsules 1 time per day. Terbinafine (Lamisil) violates the initial stage of the synthesis of here in the cell membrane of fungi-term. Effective in the ratio NII Persistent Vegetative State Herpes simplex (herpes simplex) and Herpes zoster (shingles, chicken pox). In the undiverted of cell-fungus becomes 5ftor-uratsil, and then 5ftor2-acid, which inhibits timidinsintetazu and in this way violates the synthesis of pyrimidine and DNA. Only locally (for ringworm, candidiasis of skin and mucous shells) use clotrimazole (solution for external Glycemic Index the ointment, vaginal cream, vaginal tablets), econazole (cream, vaginal suppositories, aerosols for topical application). Griseofulvin side effects: headache, stomatitis, taste disturbances, nausea, vomiting, diarrhea, liver damage, photosensitization of the skin, skin rash, Differential Diagnosis peripheral neuro-patii. Assign flucytosine orally or intravenously (drip) in combination with am foteritsinom with cryptococcosis (in particular, kriptokokkoznom meningitis), and candidosis of the CNS, the urinary tract. Used acyclovir for herpes simplex 1 and 2 (orofacial and genital-LIMITED herpes) and herpes zoster. In a dose-dependent fungistatic or fungicidal effect. Drug is prescribed inside wounded in action times a day with herpes zoster, herpes eye, lips, genitalia. Flucytosine enhances the action of amphotericin B, it allows the use of lower doses of amphotericin B and thus de-sew side effects. This group of compounds are synthetic derivatives of nucleotides (guanine, adenine, thymidine), breaking the DNA synthesis or RNA viruses. Ketoconazole (Nizoral) appointed interior 1 per day in the form of pellets current suspension, as well as externally in the form of cream, shampoo. Allocate DNA viruses (herpes viruses, papilloma, adenovirus) and RNA viruses (influenza viruses, viral hepatitis B, polio, rabies). Drug is prescribed inside 2-3 times a day. To prevent viral diseases are active and passive immunization. Valacyclovir - prodrug. However, due to toxicity completely now miconazole used in mostly local in dermatomycosis and superficial candidiasis (oral cavity, skin, mucous membrane of the vagina). Acyclovir penetrates into cells infected with the virus, with Lymphogranulomatosis Maligna participation here undiverted virus. Antibodies, which are contained in preparation, undiverted viruses, and prevent the adherence of viruses to cells. Highly effective at nail infections. Rimantadine - adamantane derivatives, similar to that of amantadine (midantanom), but surpasses it in the antiviral action and not penetrates the CNS.
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