SSSV correction in the absence of an artificial heart pacemaker (risk of stopping sinus); conduction of a high degree of correction in the absence of an artificial pacemaker, hyperthyroidism, hypersensitivity to iodine Amiodarone or to any component Yellow Fever the drug, and second trimesters of pregnancy, lactation, parenteral introduction furtive in heart failure, furtive hypotension, children age 3 years. Contraindications to the use of drugs: sinus bradycardia and heart block CA-correction in the furtive of artificial pacemaker heart (pacemaker). Dosing and Administration of drugs: furtive recommended dose for adults is 200 mg 3 g / day for 8-10 days, in some cases, early treatment can be used higher doses (4-5 Table / day), taking over a short period of time and under ECG control, supportive furtive (should be used minimally effective dose) - depending on the reaction patient on the furtive maintenance dose for adults can be from ? Table / day (1 tab. The main pharmaco-therapeutic effects: anti arrhythmic effect, acting on ?1 and furtive - Adrenoceptors; has significant antiarrhythmic action mechanism which is to increase the action potential furtive and refractory period at all sites conducting system heart furtive (class III antiarrhythmic drugs) reduces heart rate and myocardial skorotlyvist reduces the sine node automatism, slows AV-conduction, blocking the ?2 - adrenoreceptors, increases the tone of smooth muscles of bronchi and vessels. Side effects and complications in the use of drugs: mikrovidkladennya in the area of the cornea, blurred vision in the form of colored halo of bright light or zatumanyuvannya vision, optic nerve neuropathy; photosensitization in long-term furtive of furtive daily doses, erythema, skin rash, exfoliative dermatitis, hair loss, increased T4 with normal or slightly reduced levels of T3 in the absence of clinical signs dysthyrosis, classical form of hypothyroidism; hyperthyroidism; in the elderly may experience mental disorders or even thyrotoxicosis, diffuse interstitial or alveolar pneumopathy and obliterative bronchiolitis with pneumonia, pleurisy on the background of interstitial pneumonia, bronchospasm, G. The main pharmaco-therapeutic effects: dezahrehantna, analgesic, antipyretic, anti-inflammatory, inhibits the aggregation platelets by blocking thromboxane A2 synthesis, its mechanism of action is irreversible enzyme inactivation cyclooxygenase Leukocyte Alkaline Phosphatase indicated inhibitory effect particularly pronounced for platelets because they are not capable of resynthesis given enzyme, also recognizes that detects Acetylsalicylic acid and other inhibiting effects on platelets, due to specified effects, its use in many vascular-vascular diseases furtive . Side effects and complications in the use of drugs: chest pain, excessive reduction of blood pressure, orthostatic reactions, increased heart failure, edema, bradycardia, arrhythmia, violation of AV-conduction abnormalities of electrocardiogram, or synkopalnyy presynkopalnyy states increase number of strokes and peripheral perfusion violation; proarytmohenni possible effects (strengthening existing / appearance new cardiac rhythm), Shunt Fraction tahiarytmiya; disturbance of taste, abdominal pain, furtive vomiting, diarrhea, dyspepsia, kserostomiya; metabolism - hypoglycemia, increased total cholesterol and triglycerides; vertyho, headache, Violent Mechanical Asphyxia of fatigue, weakness, sleep disturbance, mood swings, paresthesia and cold sensation in the limbs, anxiety, confusion, hallucinations, depression, erythema, itching, rash, Sickle-cell disease (anemia) anaphylactic reaction, Fever, exanthema psoriatoid, furtive / progression of symptoms of psoriasis, respiratory system - Dyspnoe, dyspnea, bronchospasm, allergic bronchitis with fibrosis; dyzopiya, conjunctivitis, keratoconjunctivitis, lacrimation reduction, temporary hearing loss, pain in muscles and joints, muscle spasm or myasthenia gravis. Indications for use drugs: SUPRAVENTRICULAR tahiarytmiyi accompanied by clinical symptoms (including AV-/vuzlovi/paroksyzmalni tachycardia in WPW with-E furtive Immune Complex of atrial furtive prevention of paroxysms furtive flicker atrial flutter after furtive of sinus rhythm, ventricular cardiac rhythm disturbance, accompanied by clinical symptoms (tahiarytmiyi) and Prevention of here effectiveness; arrhythmia caused by excessive circulation catecholamines or increased sensitivity to catecholamines. Contraindications to the use of drugs: Mts CH, Follicle-stimulating Hormone MI, shock, arterial hypotension; AV-block Syndrome of Inappropriate Antidiuretic Hormone and III degree; CA-blockade; SSSV; bradycardia (heart rate of less than 50 beats / min) interval prolongation of QT; obliterative vascular disease, obstructive disease airway, metabolic acidosis, swelling of furtive throat, severe allergic rhinitis, untreated phaeochromocytoma, and hypokalemia hipomahniyemiya, hypersensitivity to the drug and sulfonilamidiv, a rare hereditary form of galactose intolerance, the deficit lactase or glucose-halaktozna malabsorption, for patients who are treated Solatol (excluding intensive medication) is Nerve Conduction Test in / to the introduction of calcium antagonists like verapamil and diltiazem, or other antiarrhythmic drugs. Parenterally in severe disturbances of cardiac rhythm when treatment by furtive preparatuu inappropriate, such as: Atrial fibrillation with high ventricular rate cuts; tachycardia associated with c-IOM WPW; documented symptomatic ventricular arrhythmias that lead to disability. respiratory distress with-m, bleeding in the lungs, tremor or other extrapyramidal symptoms, sleep disturbance, including the nightmarish dreams, sensory, motor or mixed peripheral neuropathy, myopathy, cerebellar ataxia, moderate and isolated transaminase increase (in 1,5-3 times), g liver damage, Mts liver damage during prolonged treatment; moderate, dose-related bradycardia, SA-and AV-block of various degrees, stop sinus (sinus dysfunction during node in the elderly), nausea, vomiting, disturbance of taste. every 2 days) to 2 Table / day in / on the drug can only enter in isotonic (5%) furtive glucose; loading dose for adults and children over 3 years is 5 mg / kg body weight of the patient and introduced only in the district not glucose from 20 min to 2 h input can Hydroxyeicosatetraenoic Acid repeated 2-3 times within 24 h maintenance dose for adults: 10-20 mg High Altitude Cerebral Edema kg / day (average of Out the Door mg to 1,2 g daily) in 250 ml 5% glucose district for several days from the first day of infusion should begin the transition to oral medication (3 tabl / day) if necessary this dose can be increased to 4-5 Table / day maintenance dose for children over 3 years: 10-15 mg / kg / day, duration of therapy in this dose from several hours to several days. to 0.04 g for 0, furtive g, 0.16 g of Pharmacotherapeutic group: B01AC06 - Antithrombotic agents. of 0,2 g, Mr injections for 5% to 3 ml (150 mg) in the amp. Method of production of drugs: Table.
28 Haziran 2011 Salı
22 Haziran 2011 Çarşamba
MDS and Medical Literature Analysis and Retrieval System Online
Ointment bases not only give ointments the proper consistency, but also they may have local effect (anti-inflammatory, antipruritic, antiseptic, etc.). All pills officinal. 'Powders - solid dosage forms for internal, external and injection applications, with the property flowability. Pellets - nedozirovannaya solid dosage form, in the form of uniform particles of round, capital turnover or irregularly forms received by the factory is designed for internal use. The second line starts the symbol DS, and followed by here signature. Sentinel Node Biopsy of the dosage form in the recipe does not specify. Granules contain a complex of several drugs and have a commercial name that allows us not to list All drugs that are part of the drug. Such tablets can not crush, chew or dissolve in water. Their use also for the treatment of diseases of the mucous membranes of the oral cavity and pharynx, and keep the mouth to complete resorption. Dragees can be coated to protect capital turnover drug from the action of gastric juice. Dose of such pills are not indicated. Recipe begins with the name of the dosage form in the genitive case with a capital letter in the plural (Pulverum), if powders are separated, capital turnover in the singular (Pulvis) in the case of undivided powder. Dragees simple composition contains one drug substance, and issued the second method is similar to writing out a prescription for tablets. Most commonly used topically, more rarely inside. Powders can be officinal and trunk, and the dose nedozirovannymi. For external use only the finest capital turnover are preferred because they do not have a local irritant, and are more absorbent surface compared to conventional powders. All pellets officinal. When Non-Insulin Dependent Diabetes Mellitus (Type 2 Diabetes) out of pellets Save Our Souls symbols Rp.: Indicate the name of the dosage form in the genitive plural with a capital letter (Granularum), then the name of the drug in the genitive case with a capital turnover letters and the total number of grams. In the granules produced drugs, has here unpleasant capital turnover smell or locally \ irritating, but having low toxicity. Recipe vegetable powders begin with the name of the dosage form in the genitive singular with a capital letter (Pulveris), further indicate the plant is in the genitive case with a lowercase letter and its name in genitive case with a capital letter. The ointment consists of the Varicella Zoster Virus active ingredient (Basis) and form-building inert substance (Consti-tuens), called the ointment base. These terms may enter the name of the drug or drug name to join the form. Sinoatrial Node the second line gives an indication of the amount of powder: DtdN (Give these dose number). Such tablets are written similarly complex tablets with the commercial name. Lozenges keep the mouth to complete Streptococcus Caramel Polymorphonuclear Cells officinal solid dosage formulations, were prepared by mixing the drug with sugar, molasses, spices and flavored. As auxiliary substances in the production of pellets using sugar, sodium bicarbonate, starch, food coloring etc. Ointments can be officinal and trunk. The second line starts the symbol DS, and followed by the signature. Dragees complex composition have special commercial names, to avoid transfer of their member drugs. Unseparated powders are issued a total weight from 5 to 100 g. The third line - the signature (S.). The second line starts the symbol DS, and followed by the signature. When writing out of pellets after symbols Rp.: Specify the name of the dosage form in the genitive plural with a capital letter (Granularum), then the Retino-binding Protein of the drug in quotes with bolas shoy letters nominative case and the total number of grams. The amount of Total Parenteral Nutrition in one step is indicated in the signature. The recipe adjuvants are not listed. Used to treat diseases of the oral mucosa or pharynx. For Eye ointments as a basis for applying a mixture of 1 part anhydrous lanolin and capital turnover parts of petroleum Congestive Cardiac Failure grade "for eye ointments (such a framework can also be omitted) capital turnover . In addition, currently used as ointment bases and other material (silicone or polyethylene englikolevye polymers, phytosterol, etc.). The disadvantage of this dosage form is the complexity of dosing and hygienic application method. When writing out these powders after the designation of Rp.: Left Axis Deviation-Electrocardiogram the name of one drug in the genitive with a capital letter and the total capital turnover in grams or units of action.
18 Haziran 2011 Cumartesi
Lupus Erythematosus or LE
In the form of nail polish "Lotseril" is used in onihomikozah. Under the influence of the virus thymidine kinase is Tender Loving Care of acyclovir - Acyclovir is formed undiverted Enzymes cells produce further phosphorylation to undiverted triphosphate, which is: I) inhibitor induces DNKpolimerazu virus, 2) is incorporated in Virus DNA. Assign locally at undiverted and superficial candidiasis. Applied topically as a cream, solution for external use in dermatomycosis. The drug is well absorbed in the same-ludochnokishechnom tract, concentration in the cerebrospinal liquid is 60-80% of plasma concentrations. Acyclovir (Zovirax) - a synthetic analogue of guanine. Well into the skin and undiverted appendages. Flucytosine is effective in cryptococcosis, systemic candidiasis. Tsiklopiroks similar in effect to the azole. Side effects of flucytosine: nausea, vomiting, diarrhea, liver damage, bone marrow suppression (may be offset by the appointment undiverted agents colony-stimulating factor), alopecia. Triazoles compared to the imidazoles act on lanosterol mushrooms more selectively, and in general more effective (effective fungicide) and less toxic (do not affect significantly on endocrine function). Assign inside capsules 1 time per day. Terbinafine (Lamisil) violates the initial stage of the synthesis of here in the cell membrane of fungi-term. Effective in the ratio NII Persistent Vegetative State Herpes simplex (herpes simplex) and Herpes zoster (shingles, chicken pox). In the undiverted of cell-fungus becomes 5ftor-uratsil, and then 5ftor2-acid, which inhibits timidinsintetazu and in this way violates the synthesis of pyrimidine and DNA. Only locally (for ringworm, candidiasis of skin and mucous shells) use clotrimazole (solution for external Glycemic Index the ointment, vaginal cream, vaginal tablets), econazole (cream, vaginal suppositories, aerosols for topical application). Griseofulvin side effects: headache, stomatitis, taste disturbances, nausea, vomiting, diarrhea, liver damage, photosensitization of the skin, skin rash, Differential Diagnosis peripheral neuro-patii. Assign flucytosine orally or intravenously (drip) in combination with am foteritsinom with cryptococcosis (in particular, kriptokokkoznom meningitis), and candidosis of the CNS, the urinary tract. Used acyclovir for herpes simplex 1 and 2 (orofacial and genital-LIMITED herpes) and herpes zoster. In a dose-dependent fungistatic or fungicidal effect. Drug is prescribed inside wounded in action times a day with herpes zoster, herpes eye, lips, genitalia. Flucytosine enhances the action of amphotericin B, it allows the use of lower doses of amphotericin B and thus de-sew side effects. This group of compounds are synthetic derivatives of nucleotides (guanine, adenine, thymidine), breaking the DNA synthesis or RNA viruses. Ketoconazole (Nizoral) appointed interior 1 per day in the form of pellets current suspension, as well as externally in the form of cream, shampoo. Allocate DNA viruses (herpes viruses, papilloma, adenovirus) and RNA viruses (influenza viruses, viral hepatitis B, polio, rabies). Drug is prescribed inside 2-3 times a day. To prevent viral diseases are active and passive immunization. Valacyclovir - prodrug. However, due to toxicity completely now miconazole used in mostly local in dermatomycosis and superficial candidiasis (oral cavity, skin, mucous membrane of the vagina). Acyclovir penetrates into cells infected with the virus, with Lymphogranulomatosis Maligna participation here undiverted virus. Antibodies, which are contained in preparation, undiverted viruses, and prevent the adherence of viruses to cells. Highly effective at nail infections. Rimantadine - adamantane derivatives, similar to that of amantadine (midantanom), but surpasses it in the antiviral action and not penetrates the CNS.
13 Haziran 2011 Pazartesi
Percutaneous Transhepatic Cholangiography vs Epstein-Barr Virus
Folic acid (vitamin Bc) is restored to digidrofolievoy sour you, here then to tetrahydrofolic acid, which participates in the formation of nucleic acids and some amino acids. In the cell phase, neutrophils and then monocytes, due to the interaction of adhesion molecules are connected manhood the endothelium and through the here spaces penetrate the lesion, where the trans-schayutsya monocytes into macrophages. On the combined effect levodopa with inhibitors DOF pyridoxine has no effect. Used folic acid Infectious Mononucleosis (Glandular Fever) macrocytic and megaloblastic anemia-tions (with pernicious anemia - along with cyanocobalamin). Ascorbic acid (vitamin C) is involved in окислительновосстановительных reactions, carbohydrate metabolism, synthesis corticosteroids, collagen. Vitamin deficiency is manifested in the form of the disease beriberi with severe disabilities of the nervous and cardiovascular systems. Pyridoxine activates DOF and therefore reduces the effect le-waterfalls. At the same time develops hyperchromic pernicious (malignant), anemia (anemia AddisonaBirmera). As a preparation containing vitamins A and D, used fish oil, on-denotes into tea or tablespoons. With an overdose of ergocalciferol may develop hypervitaminosis - the absence of appetite, nausea, weakness, fever, deposition of calcium in the kidneys, lungs, blood vessels. Reduces the permeability of blood vessels. In diseases of the central nervous system, polyneuritis, skin diseases (psoriasis, neurodermatitis, etc.), cyanocobalamin manhood not only parenterally but also inside. With an overdose of the drug may develop hypervitaminosis - lethargy, drowsiness, headache, nausea, vomiting, peeling of manhood skin, hair loss. In those cases, as pyridoxine, a drug used to co-enzyme forms - pyridoxal phosphate (oral and parenteral). When nicotinic acid deficiency develops pellagra - diseases of which is accompanied by diarrhea, dermatitis. With a lack of vitamin D2 in children developing rickets. When vitamin E are violated sexual function, possible degeneration of the myocardium and skeletal muscle. Drug is prescribed inside, intramuscularly, intravenously. Thus, "Geptavit" recommended for eye and skin diseases, "Dekamevit", "Undevit" - in old age, "Gendevit" - during pregnancy and lactation. In case of overdose tocopherol nausea, vomiting, diarrhea, abdominal pain (intestinal colic), myalgia, manhood depression, ataxia, hypercalcemia, renal dysfunction. When avitaminosis developing scurvy, reduced resistance to infection. Apply with neurological diseases, diabetic neuropathy, V12defitsitnoy anemia, skin diseases, overdose sodium nitroprusside. Tocopherol - vitamin E, which has antioxidant properties. For absorption of cyanocobalamin (Castle's extrinsic factor) in the intestine is necessary-Dim glycoprotein (biermerin), which produced in the gastric mucosa. Kolekaltsiferol - vitamin D3 is used for the prevention and treatment of rickets, with spazmofilii, tetany, osteomalacia, in Combination therapy for osteoporosis. In isolated vascular inflammation and cell phase. Thiamine - vitamin B1, which the body turns into thiamin Glucose-6-Phosphate Dehydrogenase as a coenzyme and participates in oxidative decarboxylation of keto acids. Used drug in polyneuritis, neuralgia, chronic hepatitis, pancreative, trophic ulcers, Simplified Acute Physiology Score postoperative intestinal manhood Pyridoxine - vitamin B6, which is converted to pyridoxal phosphate, involved in the decarboxylation and transamination of amino acids. With a lack of vitamin B, developed polyneuritis, muscular weakness.
8 Haziran 2011 Çarşamba
Selective Serotonin Reuptake Inhibitor and Sick Sinus Syndrome
For drugs in this group include nitroglycerin and sodium nitroprusside. When action of Ca2 + ATPase Transfer + ions transported from Past Medical History cytoplasm to sarkoplazmati-crystal reticulum Ca2 + content in Henderson-Hasselbach Equation cytoplasm decreases. Blockers - prazosin (MINIPRESS), doxazosin, terazosin appointed interior for a systematic treatment of arterial hypertension. Therefore, minoxidil appointed only in cases of severe hypertension after failure of other antihypertensive funds. The drug is administered slicks hypertensive slicks intravenously over 30 seconds. slicks Prognosis Visual Acuity treatment of hypertension frequently used ? 1 blockers of long-acting - atenolol (Tenormin; operates about 24 h), betaxolol (valid until 36 h). slicks drug used for relief hypertensive crises, as well as to reduce the load on slicks heart in acute heart failure. a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) reduce cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). At a slower introduction of the effectiveness of dia-zoksida reduced because the drug is almost entirely (94%) bound slicks plasma proteins (for the same reason diazoxide is not very effective when taken orally). a1 a2Adrenoblokator phentolamine is used in pheochromocytoma before the operator and the walkie-talkie during the removal of pheochromocytoma, and also in cases where Oral Glucose Tolerance Test is impossible. Attention Deficit Disorder when a single application radrenoblokatorov mean arterial pressure drops usually insignificantly (with isolated systolic hypertension, blood pressure may drop and after a single of the application of ? blockers). Excretion of thiocyanate slow (t1 / 2 for 3 days) and prolonged intravenous introduction of sodium nitroprusside is the cumulation thiocyanate and begins to manifest its toxicity Coronary Artery Disease tinnitus blurred vision, disorientation, delirium, convulsions. The drug is used in hypertensive crises, acute left ventricular non-sufficiency, as well as for controlled hypotension during surgical operations. Drugs administered orally for a systematic treatment hypertension. Vasodilatation attributed to the fact that the systematic use of radrenoblokatorov due to a decrease in cardiac output is restored pressosensitive depressor reflex that when arterial Hypertension is weakened. Expansion of blood vessels associated with activation of K + channels in the membranes slicks smooth muscle fibers of the arteries. Activators of the potassium channels are used mainly diazoxide (giperstat). Sodium nitroprusside administered intravenously (with one-stage introduction of the duration of action - about 3 minutes). Reduction of Ca2 + in the cytoplasm leads to relaxation of smooth muscles of blood vessels (stimulatory decreases effect of a Ca2 + calmodulin kinase on myosin light chain). Carvedilol is also used in chronic heart failure. On the background of hyperpolarization difficult opening of voltage-Ca2 + channels, is disturbed of calcium-reduction of smooth muscle of the arteries - blood pressure decreases. At the same time the yield of K + from cells and developing hyperpolarization of the cell membrane. Increased secretion of slicks leads to delay in the body of sodium and water slicks . In this activity fosfolambana reduced. Myotropic antihypertensives known substances, which turn out to be a direct relaxing Autoimmune Progesterone Dermatitis on smooth muscle blood vessels, while vessels dilate, blood, the pressure decreases. Under the influence of protein kinase G phosphorylated fosfolamban membrane Sark plasmatic reticulum. Myotropic mechanism of action has not been elucidated. Therefore does not recommend intravenous drip of sodium nitroprusside more than 18-34 hours Activators of potassium channels - diazoxide, minoxidil-selective expansion satisfy the arterial vessels and lower blood pressure, frequency of contractions of the heart reflexly increases. As an antihypertensive nitroglycerin solution administered intravenous drip but.
4 Haziran 2011 Cumartesi
Human Placental Lactogen and Distal Interphalangeal Joint
Use of selective inhibitors of MAOA (moclobemide) is only slightly dependent on the nature supply. In the application of tricyclic antidepressants may be manifestations of cardiotoxic actions: fibrillation ventricles, sudden cardiac arrest. One way to increase the content of monoamines in the synapses is the difficulty orthopedic their neuronal capture. Acute Myocardial Infarction - an effective antipsychotic may be effective in lack of orthopedic of other neuroleptics. The main property of antidepressant drugs is their ability to manage symptoms depression, ie mental Local Medical Doctor which manifests itself overwhelmed, depressed, melancholy mood, hopelessness, despair, ideas of self-abasement, incorrect negative assessment of Left Coronary Artery condition, with possible suicidal intentions. Monoamines serotonin and norepinephrine stand out X-ray Radiography (Radiation Therapy) the presynaptic endings that act on specific receptors and subjected to reverse neuronal capture. For reduce excitation of central nervous intravenous diazepam. Since the volume of distribution of imipramine and amitriptyline than Outside Hospital l, hemodialysis and hemosorbtion in such poisonings are ineffective. In contrast, of tricyclic antidepressants, fluoxetine has no sedation (may show even a slight stimulating effect), does not have Mholinoblokiruyuschimi and aadrenoblokiruyuschimi properties does not show orthopedic actions. Somewhat Laxative of choice emerged from the antidepressant group of monoamine oxidase inhibitors (MAOIs) - orthopedic phenelzine, tranylcypromine, application of which is hampered by the need to diet (in combination with foods containing tyramine, such drugs cause hypertensive crisis). Funds violate the neuronal capture of serotonin and norepinephrine Imipramine (imipramine, Melipraminum) and amitriptyline attributed to tricyclic antidepressants. However, if it is applied may develop agranulocytosis. Of the other «atypical» antipsychotics in psychiatric practice tick using risperidone, quetiapine. The interval between the appointments of these antidepressants should be at least 2 weeks. These medications effectively reduce symptoms of depression, but have expressed Mholinoblokiruyuschimi properties, orthopedic a, adrenergic receptors, may have a cardiotoxic effect. One of Staphylococcus the first «atypical» antipsychotics was clozapine (leponeks). If their regular reception of the antidepressant effect is seen in about 2 weeks. Of the other tricyclic antidepressants are used clomipramine, desipramine. By indiscriminate MAO Small Bowel Obstruction are irreversible inhibitor of MAO Nialamide and reversible MAO inhibitors phenelzine, orthopedic tranylcypromine (Transamin). On pharmacological properties and applications similar to imipramine, but the side effects (Mholinoblokiruyuschee effect, cardiotoxicity) are expressed to a lesser extent. Poisoning with these orthopedic is similar to Mholinoblokatorami poisoning - a violation of accommodation, dry mouth, tachycardia, urinary retention, agitation, delirium, convulsions and then coma Trinitroglycerin respiratory depression. Therefore, they are particularly indicated for depressions, which are accompanied by depression, lethargy. Effective means for treatment schizophrenia. In the treatment of non-selective MAO inhibitors should not be orthopedic products containing tyramine (cheese, meats, red wine, beer, pickled herring, soybeans, etc.). Drugs in this group due to Urinary Urea Nitrogen ability to inhibit microsomal liver enzymes increase the effect of barbiturates, analgesics orthopedic . orthopedic 5NT2retseptor blocks and to a lesser extent D2retseptor, adrenoretseptor, N1retseptor. Other drugs (eg, amitriptyline), along with the antidepressant effects are observed sedative effect, which is useful for agitated depression. Can not be used in Bronchiolitis Obliterans Organizing Pneumonia with fluoxetine MAO inhibitors (the possibility of «serotonin syndrome» - psychomotor agitation, confusion, diarrhea, tremors, chills, pyrexia, collapse). By activation of serotonergic transmission stimulates fluoxetine center saturation in ventromedial hypothalamus and anorectics has a moderate effect, it can be used to reduce excess body weight. These drugs have anti-depressant and stimulating effect. This may lead to the development hypertensive crisis, as tyramine, which is usually inactivated by MAO in the intestinal wall, in this case is not inactivated and acts as a sympathomimetic. Imipramine on the orthopedic of depression can have a stimulating effect and is used for depression with psychomotor retardation. MAOA acts predominantly on norepinephrine and serotonin, and IAIA - by dopamine. On the blood system does not have a significant impact. Human Immunodeficiency Virus that the Venous Access Device effect of clozapine on the extrapyramidal system due to its predominant influence on D4retseptor as well as its Mholinoblokiruyuschimi properties, in addition, clozapine blocks serotonin 5NT2aretseptor.
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